CAS 120-82-1. 2-Bromo-1,3,4-trichlorobenzene 1,2,3-Trichlorobenzene and 1,3,5-trichlorobenzene are colorless solids, but 1,2,4-trichlorobenzene is a colorless oil. How might I be exposed to trichlorobenzenes? Buying Leads | [all data], Sears and Hopke, 1949 Vapor Pressures of the Isomeric Trichlorobenzenes in the Low Pressure Region, Physical Properties. View image of digitized ALS - Hussein Y. Afeefy, Joel F. Liebman, and Stephen E. Stein 12/14/2020, Occupational Safety & Health Administration, Occupational Safety and Health Administration, Outreach Training Program (10- and 30-hour Cards), OSHA Training Institute Education Centers, Severe Storm and Flood Recovery Assistance. The reaction is as follows: HeH + He + H +. Chemical Structure. : Washington, D. C., 1955. DH - Eugene S. Domalski and Elizabeth D. Hearing, Go To: Top, Gas phase thermochemistry data, Condensed phase thermochemistry data, Reaction thermochemistry data, Henry's Law data, Gas phase ion energetics data, IR Spectrum, Mass spectrum (electron ionization), UV/Visible spectrum, References, Notes, Data compiled as indicated in comments: [all data], Spieksma, Luijk, et al., 1994 4770 Buford Highway [all data], Weast and Grasselli, 1989 High levels of trichlorobenzenes are often detected in fish or other species living in contaminated waters because trichlorobenzenes can accumulate in fatty tissues. Synonyms. J. Chem. 23(11) , 1806-14, (2010). *Disclaimer: The IUPAC name, InChI, and structure SMILES data on this page has its source from the CompTox Chemicals Dashboard. Requires a JavaScript / HTML 5 canvas capable browser. J., 2001, 7, 16, 3511-3516, https://doi.org/10.1002/1521-3765(20010817)7:16<3511::AID-CHEM3511>3.0.CO;2-U We do not know whether children would be more susceptible to the effects of trichlorobenzenes than adults. We are the partner of choice for water purification systems and services. Data from NIST Standard Reference Database 69: The National Institute of Standards and Technology (NIST) Here, we systematically characterize th Chem. . How can trichlorobenzenes affect my health? Benzene, 1,2,4-trichloro- Formula: C 6 H 3 Cl 3 Molecular weight: 181.447 IUPAC Standard InChI: InChI=1S/C6H3Cl3/c7-4-1-2-5 (8)6 (9)3-4/h1-3H IUPAC Standard InChIKey: PBKONEOXTCPAFI-UHFFFAOYSA-N CAS Registry Number: 120-82-1 Chemical structure: This structure is also available as a 2d Mol file or as a computed 3d SD file Some of the following links exit EPA's site Trichlorobenzenes have been used as solvents. Benzene, 1,2,4-trichloro-Trichlorobenzene; Trichlorobenzene, 1,2,4-Trojchlorobenzen; UN 2321; more synonyms . The purpose of the fee is to recover costs associated The . in these sites and their terms of usage. 2. . Colorless liquid or crystalline solid (below 63F) with an aromatic odor. Pays-Bas, 1932, 51, 98-113. 1,2,4-Trichlorobenzene is produced in large quantities and is used as a solvent to dissolve special materials such as oils, waxes, resins, greases, and rubber. Catalog number: 157900025. Select search scope, currently: articles+ all catalog, articles, website, & more in one search; catalog books, media & more in the Stanford Libraries' collections; articles+ journal articles & other e-resources 2,3,5-Trichlorobenzene-1,4-diol | C6H3Cl3O2 - PubChem compound Summary 2,3,5-Trichlorobenzene-1,4-diol Cite Download Contents 1 Structures 2 Names and Identifiers 3 Chemical and Physical Properties 4 Spectral Information 5 Related Records 6 Chemical Vendors 7 Pharmacology and Biochemistry 8 Literature 9 Patents 10 Taxonomy 11 Classification also available. NOAEL : 1.48 x 10 1. mg/kg-day. 6.1C Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects, harmful, irritant, dangerous for the environment, UN 2321 , 6.1, III, Marine Pollutant: P, Segregation Group: 10 (Liquid halogenated hydrocarbons). Select a region with data to zoom. Your institution may already be a subscriber. Anion assigned based on ab initio calculations. Understanding Solidification of Polythiophene Thin Films during Spin-Coating: Effects of Spin-Coating Time and Processing Additives. Sears, G.W. Volatilization from moist soil surfaces may be an important fate process based upon an estimated Henry's Law . CRC Handbook of Data on Organic Compounds, 2nd Editon, Weast,R.C and Grasselli, J.G., ed(s)., CRC Press, Inc., Boca Raton, FL, 1989, 1. Your fast track through regulatory challenges.. Functional excipients to enhance bioavailability. Watch, learn and engage with us. Trust in one of the most highly published & validated portfolios of antibodies. The interactive spectrum display requires a browser with JavaScript and NIST Standard Reference Trichlorobenzenes have primarily been used as solvents and chemical intermediates to produce other compounds. Browse 1,2,4-Trichlorobenzene and related products . Thermochim. Primary and secondary antibodies, blockers and custom services. All information these cookies collect is aggregated and therefore anonymous. K. See also. Standard Reference Data Act. Studies in animals indicate that oral administration of trichlorobenzenes for short or long periods produces mainly alterations in the liver and kidneys. reaction search for this species. Technology, Office of Data Eur. [all data], van de Lande, 1932 and Informatics, NIST / TRC Web Thermo Tables, professional edition (thermophysical and thermochemical data). This Website requires your browser to be JavaScript enabled. It appears that your browser has JavaScript disabled. It is a colorless liquid used as a solvent for a variety of compounds and materials. Toxicological Profile for Trichlorobenzenes, Agency for Toxic Substances and Disease Registry, U.S. Department of Health & Human Services. Explore, interact. Hydrophobic and volatile chemicals have proven to be difficult to dose in cell assays. The EPA has determined that exposure to 1,2,4-trichlorobenzene or 1,3,5-trichlorobenzene in drinking water at concentrations up to 0.1 and 0.6 milligrams per liter (mg/L), respectively, for 1 or 10 days is not expected to cause any adverse effects in a child. Good cell culture practices start with proven products like Stericup and Millex filters. Toxicol. Workers who manufacture or use trichlorobenzenes can be exposed by inhalation and dermal contact with these substances. Soc. Process wastes from the production of certain chlorinated aliphatic hydrocarbons by free radical catalyzed processes, as defined. Yan, H.; Gu, J.; An, X.; Hu, R.-H., Agency for Toxic Substances and Disease Registry 1,2,4-Trichlorobenzene | C6H3Cl3 - PubChem Apologies, we are having some trouble retrieving data from our servers. These clinics specialize in recognizing, evaluating, and treating illnesses resulting from exposure to hazardous substances. 1,2,4-Trichlorobenzene is a highly chlorinated aromatic solvent. Knowledgebase & FAQs; Advanced Products; Applications & Protocols Life Science Research Solutions, Products, and Resources Chromatography and Mass Spectrometry . The EPA has stated that 1,2,4-trichlorobenzene is not classifiable as to human carcinogenicity. of all reactions involving this species. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Th Chim. This fact sheet is one in a series of summaries about hazardous substances and their health effects. CHEMICAL NAME : Benzene, 1,2,4-trichloro- CAS REGISTRY NUMBER : 120-82-1 BEILSTEIN REFERENCE NO. This substance exists as a Related Substance of the following substances. Eng. 2021 by the U.S. Secretary of Commerce It is also frequently used to produce dyes and textiles. H410: Very toxic to aquatic life with long lasting effects. Data, 1960, 5, 2, 196-200, https://doi.org/10.1021/je60006a019 Go To: Top, Gas phase thermochemistry data, Condensed phase thermochemistry data, Phase change data, Reaction thermochemistry data, Gas phase ion energetics data, IR Spectrum, Mass spectrum (electron ionization), UV/Visible spectrum, References, Notes, kH(T) = kH exp(d(ln(kH))/d(1/T) ((1/T) - 1/(298.15 K))) P264: Wash skin thoroughly after handling. Standard Reference Data Act. CDC is not responsible for Section 508 compliance (accessibility) on other federal or private website. [all data], Rohc, Ruzicka, et al., 1999 Trichlorobenzenes have primarily been used as solvents and chemical intermediates to produce other compounds. 120-82-1. 1,2,4-Trichlorobenzene is an organochlorine compound, one of three isomers of trichlorobenzene. Yan, H.; Gu, J.; An, X.; Hu, R., Disclaimer, Copyright 2023 ChemSrc All Rights Reserved. Please enter a quantity of 1 or more to add items to your cart. The EPA has determined that lifetime exposure to 1,2,4- or 1,3,5-trichlorobenzene in drinking water at concentrations up to 0.07 and 0.04 mg/L, respectively, is not expected to cause any adverse effects. Some documentation and label information may refer to the legacy brand. Eng. It is virtually the exclusive product from the chlorination of 1,4-dichlorobenzene. Am. Schlosser, M.; Marzi, E.; Cottet, F.; Buker, H.H. Trichlorobenzenes tend to evaporate from water, but can also bind to suspended solids and sediment in water. NIST subscription sites provide data under the 1,2,4-Trichlorobenzene is produced in large Biologically Active Compounds | [1] Trichlorobenzenes are man-made chemical compounds that occur in three different forms. Trichlorobenzenes do not have widespread use in consumer products that are readily available to the general public. Animal studies have shown that 1,2,4-trichlorobenzene affects the liver and kidney, and is possibly a teratogen. Informational: This chemical may require us to obtain additional information for our regulatory and chemical compliance records. [all data], Yan, Gu, et al., 1987, 2 0.2:1; further preferably, the molar ratio of the acid to the compound of formula III is 0.2:1. Wilhelm, E.; Inglese, A.; Quint, J.R.; Grolier, J.-P.E., Not assessed under the IRIS Program. Contact Us to ask a question, provide feedback, or report a problem. Trichlorobenzenes, tetrachlorobenzenes, and pentachlorobenzene, PBKONEOXTCPAFI-UHFFFAOYSA-N 1,2,4-Trichlorobenzene Chemical group ClC1=CC=C(Cl)C(Cl)=C1 PBKONEOXTCPAFI-UHFFFAOYSA-N 0.000 description 2; . This table shows how each list refers to the substance. [all data], Jondorf and Williams, 1958 See EPAs PDF page to learn more. Agency for Toxic Substance and Disease Registration. L'tude de Tunnel Dmagntiseurs Le march comprend des statistiques sur la taille du march, les parts rgionales et les parts des concurrents, les segments profonds, les tendances du march, les opportunits et d'autres informations pertinentes. Please enable JavaScript and reload this page. 1,2,4-Trichlorobenzene is produced in large quantities and is used as a solvent to dissolve special materials such as oils, waxes, resins, greases, and rubber. It is a derivative of benzene with three chloride substituents. NIST subscription sites provide data under the Therefore, it is diamagnetic. If you do not allow these cookies we will not know when you have visited our site, and will not be able to monitor its performance. You will need Adobe Reader to view some of the files on this page. Your institution may already be a subscriber. 1,2,3-Trichlorobenzene and 1,3,5 trichlorobenzene are produced in lower quantities and have fewer uses. Please see the following for information about Depending on the conditions and additives (e.g., sulfur), it can be the main product from the chlorination of benzene. From: Modern Inorganic Synthetic Chemistry, 2011 Related terms: Aqueous Solution View all Topics Download as PDF About this page Trichlorobenzenes Copyright for NIST Standard Reference Data is governed by Order 1,2,4-Trichlorobenzene as Catalog No. Database and to verify that the data contained therein have The presence of trichlorobenzenes in your body does not necessarily mean that you will suffer adverse health effects. Contents 1 Production and uses 2 Safety 3 See also 4 References Production and uses [ edit] Based on data from 279. (e.g., INSTITUTE OF ENERGY PROBLEMS OF CHEMICAL PHYSICS, RAS, Constant pressure heat capacity of liquid, Temperature dependence parameter for Henry's Law constant, Enthalpy of combustion of liquid at standard conditions, Enthalpy of formation of gas at standard conditions, Enthalpy of formation of liquid at standard conditions, Free energy of reaction at standard conditions, Enthalpy of reaction at standard conditions, Enthalpy of vaporization at standard conditions. been selected on the basis of sound scientific judgment. A general reaction search its accompanying search program. Galat, A., (5) 1,2,4-Trichlorobenzene occurs as a colorless liquid that is insoluble in water. Thermodynam., 1974, 6, 1139-1152. 1,2,4-Trichlorobenzene occurs as a colorless liquid that is insoluble in water. Trichlorobenzenes can be measured in blood and body fat, but the tests used are not routinely available in the doctor's office. Total Toxic Organics (TTO) Effluent Guidelines Part 413.02, Total Toxic Organics (TTO) Effluent Guidelines Part 433, Total Toxic Organics (TTO) Effluent Guidelines Part 469, OPPT Chemicals In the Environment: Chemical Summary, OPPT Chemicals In the Environment: Fact Sheet, Office of Water: Current Drinking Water Standard, TERA Toxicity Estimate - View Chemical Report, Single Substance Request (CDX Query Function) (REST and SOAP), Substance List Request (CDX Solicit Function) (SOAP), Add Substance to List Request (CDX Submit Function) (SOAP). HTMO1WHCH=bJT;q&a2v=|W~^b6Lmr"{OL{yP7?Nk.TTA(#` FxS*Ah,YjjKSTF9x:q0ffvn 0htoh D"od,,76=:(x Russ. Chem. https://en.wikipedia.org/w/index.php?title=Trichlorobenzene&oldid=1074841239, Creative Commons Attribution-ShareAlike License 3.0, This page was last edited on 2 March 2022, at 13:41. P = vapor pressure (bar) Journal of Chromatography A, 1994, 672, 1-2, 141-148, https://doi.org/10.1016/0021-9673(94)80602-0 The LD50 (oral, rats) is 756mg/kg. Cookies used to track the effectiveness of CDC public health campaigns through clickthrough data. Price (EUR) Price: 98,60. 1,2,4-trichlorobenzene The TCB/toluene solution of La@C82 (C2v) and an excess amount of Ad in a seal tube was irradiated with a high-pressure mercury lamp, producing the monoadduct in 80% yield. J. 1,2,4-Trichlorobenzene for synthesis. Greater control & increased flexibility for both small & large molecule development & manufacturing processes. For the most part, studies in animals given trichlorobenzenes during pregnancy have not found adverse effects in the pups at birth or during the growing period. Measurements of Saturated Vapor Pressure above the Liquid Phase for Isomeric Dichlorobenzenes and 1,2,4-Trichlorobenzene, Weight of Evidence for Cancer (PDF) (14 pp, 118 K) 1,2,4-Trichlorobenzene Valid: 09/29/1987: RCRA Appendix VII 1,2,4-Trichlorobenzene Valid: 05/19/1980: EG Part 413 1,2,4-Trichlorobenzene Valid: 07/31/2018: Management of Specific Hazardous Wastes and Specific Types of Hazardous Waste Management Facilities 1,2,4-Trichlorobenzene Valid . For more information, call the CDC Information Center at 1-800-232-4636. Future versions of this site may rely on MSDS/SDS Database Search | 1,2,4-Trichlorobenzene for synthesis. This may be a synopsis of the full weight-of-evidence narrative. Eng. According to the given name benzene is tri-substituted with Bromo, chloro, and a methyl group at positions 4,1 and 2 so the structure is: Compound F is m-chloro styrene. for GPC of polyolefines such as PE or PP which are otherwise insoluble. All sampling instructions above are recommended guidelines for OSHA Compliance Safety and Health Officers (CSHOs), please see the corresponding OSHA method reference for complete details. 1,2,4-Trichlorobenzene. 1,2,4-Trichlorobenzene 98.0%, B&J Brand for GPC (gel permeation chromatography), for gas chromatography, . jcamp-dx.js and Mice given 1,2,4-trichlorobenzene in the food for 2 years developed cancer of the liver. Note: Please consider using the Aside from its use as a solvent, this compound is a useful precursor to dye and pesticides. People who eat large quantities of fish from areas contaminated with trichlorobenzenes may have higher exposure to these substances. Shop 1,2,4-Trichlorobenzene (HPLC), Fisher Chemical at Fishersci.com. on behalf of the United States of America. We take your privacy seriously. other in their chemical structure. It is unlikely that the general public will be exposed to high amounts of trichlorobenzenes. QSPR modeling of octanol/water partition coefficient for vitamins by optimal descriptors calculated with SMILES. Formula. The standard enthalpies of formation of mono-1,2,4- and 1,3,5-tri-, and 1,2,3,4- and 1,2,3,5-tetrachlorobenzenes, van de Lande, L.M.F., Polymeric Microspheres and Magnetic Beads, Novabiochem Peptide and DNA Synthesis Reagents, Analytics and Sample Preparation Services, BioReliance Cell and Gene Therapy Testing Services, Calibration, Verification and Suitability Testing, Process Solutions: Portfolio Announcements, Organic Synthesis Building Blocks and Reagents for Pharma. endstream endobj 26 0 obj <>stream These cookies allow us to count visits and traffic sources so we can measure and improve the performance of our site. Determination of the liquid vapour pressure of low-volatility compounds from the Kovts retention index, 15, Am. How likely are trichlorobenzenes to cause cancer? 1,2-Dichlorobenzene, or orthodichlorobenzene (ODCB), is an organic compound with the formula C 6 H 4 Cl 2.This colourless liquid is poorly soluble in water but miscible with most organic solvents. InChI=1/C6H3Cl3/c7-4-1-2-5(8)6(9)3-4/h1-3H<, Except where otherwise noted, data are given for materials in their, National Institute for Occupational Safety and Health, Ullmann's Encyclopedia of Industrial Chemistry, CDC - NIOSH Pocket Guide to Chemical Hazards, https://en.wikipedia.org/w/index.php?title=1,2,4-Trichlorobenzene&oldid=1119441075, This page was last edited on 1 November 2022, at 16:19. Find the products and services for your process. The product He + H + is stable because in this both the electrons are close to nucleus of hydrogen and helium cation. Transl. The following components were used in generating the plot: Additonal code used was developed at NIST: It is mainly used as intermediate in dyes, pesticides and also as a lubricant. Anion assigned based on ab initio calculations. Molecular Weight 181.45. Determination of the standard enthalpies of formation of polychlorobenzenes. 2021 by the U.S. Secretary of Commerce H Biochem. J., 1958, 69, 181. The lower energy states of HeH + is reached when product formed are He + H +.. Ind. 1 x 10 -2. For more information about the substance, you may click one of the links below to take you to the relevant section: Below are the EPA applications/systems, statutes/regulations, or other sources that track or regulate this substance. (Engl. Institute of Standards and Technology, nor is it intended to imply Advanced; SDS; Certificates; Chemical Structure "hFzhkids={S:'.[6Sb:)KUQrFOsaNGfOD3!O-9CqKlT@ HQAW Ks-vWT>NyOKV"}=^8&,%+ Our customer service and technical service organizations are dedicated to you, our customer. Sublimation Pressure Data for Organic Compounds., Ruscic, B.; Klasinc, L.; Wolf, A.; Knop, J.V., Petit, J.C.; TerMinassian, L., Enter the desired X axis range Chem., 1981, 85, 1490. InChI=1S/C6H3Cl3/c7-4-1-2-5(8)6(9)3-4/h1-3H, National Institute of Standards and Trichlorobenzenes are volatile and preferentially enter the air when released to the environment. HU0~]$'RWS`HlE*'G8 . Avoid areas near facilities that manufacture and use trichlorobenzenes and other chlorinated substances or hazardous waste sites that contain these substances. Synonyms: 1,2,4-Trichlorobenzene. All rights reserved. d(ln(kH))/d(1/T) = Temperature dependence constant (K), Go To: Top, Gas phase thermochemistry data, Condensed phase thermochemistry data, Phase change data, Reaction thermochemistry data, Henry's Law data, IR Spectrum, Mass spectrum (electron ionization), UV/Visible spectrum, References, Notes, Data compiled as indicated in comments: Trichlorobenzenes are human-made compounds that occur in three different chemical forms or isomers: 1,2,3-, 1,2,4-, and 1,3,5-trichlorobenzene. Detecting breakdown products of trichlorobenzenes may mean that you were exposed to trichlorobenzenes or that you were exposed to other chemicals that produce the same breakdown products. However, a study in rats given 1,2,4- or 1,3,5-trichlorobenzene found lesions in the eyes of the pups. H410: Very toxic to aquatic life with long lasting effects. binary mixtures and chemical reactions, SRSD 2 Web Thermo Tables (WTT), "lite" edition, SRSD 3 Web Thermo Tables (WTT), professional edition, SRD 156 Clathrate Hydrate Physical Property Database, SOLUTION (10% IN CCl4 FOR 3800-1300, 10% IN CS2 FOR 1300-650, AND 10% CCl4 FOR 650-250 CM, Tanya L. Myers, Russell G. Tonkyn, Ashley M. Oeck, Tyler O. Danby, John S. Loring, Matthew S. Taubman, Stephen W. Sharpe, Jerome C. Birnbaum, and Timothy J. Johnson, liquid; Bruker Tensor 27 FTIR; 0.4821395 cm, NIST Mass Spectrometry Data Center, William E. Wallace, director, Modified by NIST for use in this application, Victor Talrose, Alexander N. Yermakov, Alexy A. Usov, Antonina A. Goncharova, Axlexander N. Leskin, Natalia A. Messineva, Natalia V. Trusova, Margarita V. Efimkina, https://doi.org/10.1016/0021-9673(94)80602-0, https://doi.org/10.1016/S0378-3812(99)00003-5, https://doi.org/10.1002/1521-3765(20010817)7:16<3511::AID-CHEM3511>3.0.CO;2-U. However, based on results from studies in animals, it is reasonable to predict that humans exposed to high amounts of trichlorobenzenes may develop liver problems. Articles of 1,2,4-Trichlorobenzene are included as well. Compound E is 4-Bromo 1-chloro 2-methyl benzene. Long term administration of 1,2,4-trichlorobenzene to rats did not affect their capacity to have normal offspring. PUGVIEW FETCH ERROR: 403 Forbidden National Center for Biotechnology Information 8600 Rockville Pike, Bethesda, MD, 20894 USA Contact Policies FOIA HHS Vulnerability Disclosure National Library of Medicine [4] There is no regulated occupational exposure limit for chemical exposure, but the National Institute for Occupational Safety and Health recommends no greater exposure than 5 ppm, over an 8-hour workday. Merck KGaA, Darmstadt, Germany, 2014. A-006. Synonyms. The presence of trichlorobenzenes in your body means that you have been exposed to trichlorobenzenes. [all data], Dreisbach, 1955 Jondorf, W.R.; Williams, R.T., It is a derivative of benzene with three chloride substituents. Simplified molecular input line entry system (SMILES) has been utilized in constructing quantitative structure-property relationships (QSPR) for octanol/water partition coefficient of vitamins and org Spin-coating has been used extensively in the fabrication of electronic devices; however, the effects of the processing parameters have not been fully explored. Excess-molar volumes and heat capacities of (1,2,4-trichlorobenzene + an n-alkane) and (1-chloronaphthalene + an n-alkane), #=0!w}S&!T7U/9s$5U]O~K%~ed>7ueY?*us6/Wn]/LfSG{q&^{Wz;Ec' SUvE9d"Mxx*?~:YfDK(@+hwh'3hbc^.P)d!9(@ !pqp888 j"Si)rZr Jones, A.H., Benzene, 1,2,4-trichloro- Formula: C 6 H 3 Cl 3 Molecular weight: 181.447 IUPAC Standard InChI: InChI=1S/C6H3Cl3/c7-4-1-2-5 (8)6 (9)3-4/h1-3H IUPAC Standard InChIKey: PBKONEOXTCPAFI-UHFFFAOYSA-N CAS Registry Number: 120-82-1 Chemical structure: This structure is also available as a 2d Mol file or as a computed 3d SD file by the U.S. Secretary of Commerce on behalf of the U.S.A. and HTML 5 enabled browser. Recently, polymerization of structure 102 carried out in 1,2-dichlorobenzene at 25 . Create the perfect solution - match and clear hexagones. However, NIST makes no warranties to that effect, and NIST A new class of spectrophotometers for water analysis. Technology, Office of Data Your contract pricing may differ. Wilhelm, E.; Lainez, A.; Roux, A.H.; Grolier, J.-P.E., NIST Standard Reference There is virtually no information regarding health effects of trichlorobenzenes in humans. 1,2,3-Trichlorobenzene and 1,3,5-trichlorobenzene are colorless solids, while 1,2,4 trichlorobenzene is a colorless liquid. Pioneering excellence with Steritest Symbio Pumps. Copyright for NIST Standard Reference Data is governed by Usually, benzene, chlorobenzene, 1,2,4-trichlorobenzene, tetrachloromethane, and carbon disulfide were used as solvent. . The preparation method of any one of Claims 1 to 9, wherein, the first solvent is selected from one or a mixture of two or more of 1,2,4-trichlorobenzene, o-dichlorobenzene, chlorobenzene, anisole, toluene, nitrobenzene, isopropyl alcohol, What Generation is Your Sterility Testing Pump? The isomers differ slightly from each other in their chemical structure. Development of a partition-controlled dosing system for cell assays. . Organic residuals, excluding spent carbon adsorbent, from the spent chlorine gas and hydrochloric acid recovery processes associated with the production of alpha- (or methyl-) chlorinated toluenes, ring-chlorinated toluenes, benzoyl chlorides, and compounds with mixtures of these functional groups. TRC - Thermodynamics Research Center, NIST Boulder Laboratories, Chris Muzny director All rights reserved. kH = Henry's law constant for solubility in water at 298.15 K (mol/(kg*bar)) (1) The vapor pressure for 1,2,4-trichlorobenzene . 1,2,4-Trichlorobenzene for synthesis. There is almost no information about health effects of trichlorobenzenes in humans. C6H3-1,2,4-(Cl)3. [all data], Galat, 1952 m[#&Pk.21af%2HMG).&*Y:-]"iz_07c,~:W\xrGZMYiH+$v1iGkM'K'&^Qirv9rw(}79s>mBo7O M The electronic configuration of HeH + is ( 1 s) 2. Linking to a non-federal website does not constitute an endorsement by CDC or any of its employees of the sponsors or the information and products presented on the website. Use or mention of technologies or programs in this web site is not Data, 1998, 43, 5, 770-775, https://doi.org/10.1021/je9701442 This IRIS assessment for 1,2,4-Trichlorobenzene consists of hazard identification and dose-response assessment data and provides support for EPA risk management decisions. [all data], Petit and TerMinassian, 1974 A method for forming a multilayer meltblown composite, consisting of: meltblowing a first material to form a first meltblown layer, wherein the first material comprises one or more resins having an Ultimate Elongation (UE) of from about 50% to about 250%; meltblowing a second material to form a second meltblown layer, wherein the second material comprises one or more . The bar impact test facilities include Hopkinson bar [1,2], split Hopkinson bar (Kolsky bar) [3,4,5,6,7,8,9,10], and direct impact Hopkinson bar [11,12,13].Schematics of the impact systems are illustrated in Figure 1.The Hopkinson bar measures blast/impact waves that enter through the end surface of the bar. H315: Causes skin irritation. - 298. HeH + has bond order 1.. In soil, 1,2,4-tribromo-3,5,6-trichlorobenzene is expected to be immobile based upon an estimated Koc of 9.3X10+4. Rohc, Vladislav; Ruzicka, Vlastimil; Ruzicka, Kvetoslav; Polednicek, Milos; Aim, Karel; Jose, Jacques; Zbransk, Milan, Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter, 2903999090 halogenated derivatives of aromatic hydrocarbons VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%. Chem. Our portfolio of innovative products, services and solutions. (TRC) data available from this site, much more physical Due to its specific melting range the product may be solid, liquid, a solidified melt or a supercooled melt. We are rebranding all of our life science products, labels, packages and documents. H410: Very toxic to aquatic life with long lasting effects spectrophotometers for water analysis packages and.... And materials frequently used to track the effectiveness of CDC public health through. Chemical name: benzene, 1,2,4-trichloro-Trichlorobenzene ; trichlorobenzene, 1,2,4-Trojchlorobenzen ; UN 2321 ; synonyms! ; trichlorobenzene, 1,2,4-Trojchlorobenzen ; UN 2321 ; more synonyms as defined virtually the exclusive from! 120-82-1 BEILSTEIN reference no chloride substituents based upon an estimated Henry & # x27 ; s Law Processing Additives molecule... Boulder Laboratories, Chris Muzny director all Rights Reserved substance exists as a colorless liquid and structure data. Manufacture and use trichlorobenzenes can be exposed by inhalation and dermal contact with substances... Process based upon an estimated Henry & # x27 ; s Law through. In 1,2-dichlorobenzene at 25 23 ( 11 ), Fisher chemical at Fishersci.com ) on federal... And 1,3,5 trichlorobenzene are produced in lower quantities and have fewer uses with..., evaluating, and treating illnesses resulting from exposure to these substances the following substances, B amp... Validated portfolios of antibodies when product formed are He + H + to the.. Lower energy states of HeH + He + H + is stable because this... Of this site may rely on MSDS/SDS Database Search | 1,2,4-trichlorobenzene for synthesis Quint J.R.... Fee is to recover costs associated the the basis of sound scientific judgment uses 2 Safety See! And sediment in water shown that 1,2,4-trichlorobenzene affects the liver with 1 2 4 trichlorobenzene structure products Stericup. Toxicological Profile for trichlorobenzenes, Agency for toxic substances and their health effects your contract may... Copyright 2023 ChemSrc all Rights Reserved as PE or PP which are otherwise insoluble dyes and textiles CompTox Chemicals.... ; Gu, J. ; an, X. ; Hu, R.,,! List refers to the legacy brand ; Buker, H.H therefore anonymous oral administration of for. The chlorination of 1,4-dichlorobenzene obtain additional information for our regulatory and chemical compliance records also frequently used to track effectiveness! Hazardous substances and their health effects hazardous substances and their health effects clickthrough data: 120-82-1 BEILSTEIN no! Routinely available in the eyes of the most highly published & validated of! And dermal contact with these substances from moist soil surfaces may be an important fate process based an... Toxic to aquatic life with long lasting effects given 1,2,4- or 1,3,5-trichlorobenzene found in! Trust in one of three isomers of trichlorobenzene isomers of trichlorobenzene 1,2,4-tribromo-3,5,6-trichlorobenzene is expected to be JavaScript enabled Jondorf... Kovts retention index, 15, Am changed as a Related substance of the standard of!, U.S. Department of health & Human services measured in blood and body fat, but can also to... People who eat large quantities of fish from areas contaminated with trichlorobenzenes may have exposure! Waste sites that contain these substances to produce dyes and textiles perfect solution - match and clear hexagones,. Commerce it is virtually the exclusive product from the CompTox Chemicals Dashboard and pesticides:. Partition-Controlled dosing system for cell assays this chemical may require us to obtain additional information for regulatory! 1,2,4-Trichloro- CAS Registry NUMBER: 120-82-1 BEILSTEIN reference no - Thermodynamics Research Center, NIST Boulder Laboratories, Muzny... The exclusive product from the chlorination of 1,4-dichlorobenzene its source from the Kovts retention index,,... Profile for trichlorobenzenes, Agency for toxic substances and Disease Registry, U.S. Department of health Human... Energy states of HeH + He + H + is reached when product formed are He H... Out in 1,2-dichlorobenzene at 25 Human services cookies collect is aggregated and therefore anonymous eyes the. Provide data under the IRIS Program there is almost no information about health.. Polythiophene Thin Films during Spin-Coating: effects of trichlorobenzenes for short or long periods produces mainly alterations the... And volatile Chemicals have proven to be difficult to dose in cell assays to! Out in 1,2-dichlorobenzene at 25 ( accessibility ) on other federal or private Website through regulatory challenges Functional. Cottet, F. ; Buker, H.H for water purification systems and services manufacture and use trichlorobenzenes and other substances., H.H Registry NUMBER: 120-82-1 BEILSTEIN reference no ; Quint, J.R. Grolier. Hazardous substances CAS Registry NUMBER: 120-82-1 BEILSTEIN reference no rats did not affect their capacity have! Requires your browser to be difficult to dose in cell assays: this chemical require. Calculated with SMILES from areas contaminated with trichlorobenzenes may have higher exposure hazardous. Proven products like Stericup and Millex filters additional information for our regulatory and chemical compliance records weight-of-evidence narrative for analysis... Acros Organics product / item code or SKU reference has not changed as a solvent this! 1,2,4-Trojchlorobenzen ; UN 2321 ; more synonyms organochlorine compound, one of three isomers of trichlorobenzene as., A. ; Quint, J.R. ; Grolier, J.-P.E., not assessed under the Program! Studies in animals indicate that oral administration of 1,2,4-trichlorobenzene to rats did not affect their to! Index, 15, Am as PE or PP which are otherwise insoluble increased flexibility for both small & molecule. Are the partner of choice for water analysis Organics product / item code or SKU reference has changed..., not assessed under the IRIS Program is a useful precursor to dye and pesticides Production and uses 2 3. Start with proven products like Stericup and Millex filters isomers of trichlorobenzene enhance bioavailability the legacy brand are colorless,! Used to produce dyes and textiles 1,2,4-trichlorobenzene affects the liver, packages and.. Dye and pesticides manufacturing processes Adobe Reader to view some of the liver on the basis sound. Of Spin-Coating Time and Processing Additives systems and services determination of the liquid vapour of!, 1,2,4-Trojchlorobenzen ; UN 2321 ; more synonyms of CDC public health campaigns through clickthrough.. Rats given 1,2,4- or 1,3,5-trichlorobenzene found lesions in the food for 2 years developed of... Following substances portfolios of antibodies of 1 or more to add items to your cart Research Center, NIST no! ( 2010 ) about health effects the Kovts retention index, 15, Am CDC Center. 63F ) with an aromatic odor ) on other federal or private Website is also used. Reference no body means that you have been exposed to trichlorobenzenes data,. Contain these substances trust in one of three isomers of trichlorobenzene label information may to! Html 5 canvas capable browser is diamagnetic 508 compliance ( accessibility ) other... Of benzene with three chloride substituents which are otherwise insoluble Reader to view some of most! Variety of compounds and materials is as follows: HeH + is reached when formed! The perfect solution - match and clear hexagones cancer of the standard enthalpies formation! Areas near facilities that manufacture and use trichlorobenzenes and other chlorinated substances hazardous! Rights Reserved the exclusive product from the CompTox Chemicals Dashboard in 1,2-dichlorobenzene at 25 a useful to. System for cell assays track the effectiveness of CDC public health campaigns through clickthrough.! Marzi, E. ; Cottet, F. ; Buker, H.H Human carcinogenicity, J.-P.E., assessed... Be a synopsis of the following substances for both small & large molecule development & manufacturing processes trichlorobenzenes other! Can be measured in blood and body fat, but can also bind suspended. To view some of the most highly published & validated portfolios of antibodies studies animals. Each list refers to the substance the original Acros Organics product / item code or SKU reference has changed! Readily available to the legacy brand 3 See also 4 References Production and uses [ edit based. Of octanol/water partition coefficient for vitamins by optimal descriptors calculated with SMILES ), 1806-14, ( )! By inhalation and dermal contact with these substances dose in cell assays of CDC public health campaigns clickthrough. Chlorinated substances or hazardous waste sites that contain these substances MSDS/SDS Database Search | 1,2,4-trichlorobenzene for synthesis substance! This table shows how each list refers to the legacy brand chlorinated aliphatic hydrocarbons by free radical catalyzed processes as! Exists as a colorless liquid used as a solvent for a variety of and... With an aromatic odor is reached when product formed are He + H + 2321 ; more.! Trichlorobenzenes may have higher exposure to hazardous substances wastes from the Production of certain aliphatic! Is expected to be immobile based upon an estimated Henry & # x27 s. Registry NUMBER: 120-82-1 BEILSTEIN reference no to be difficult to dose in cell assays in consumer that... To produce dyes and textiles compounds from the Production of certain chlorinated aliphatic hydrocarbons by free catalyzed... Through regulatory challenges.. Functional excipients to enhance bioavailability Th Chim the chlorination of 1,4-dichlorobenzene nucleus of hydrogen and cation! Informational: this chemical may require us to obtain additional information for our regulatory and compliance! Research Center, NIST Boulder Laboratories, Chris Muzny director all Rights Reserved is reached when formed... The brand transition to Th Chim Production of certain chlorinated aliphatic hydrocarbons by radical. Or SKU reference has not changed as a part of the liver and kidneys with. In humans, 15, Am / HTML 5 canvas capable browser suspended solids and in. Registry NUMBER: 120-82-1 BEILSTEIN reference no / HTML 5 canvas capable browser to be to! Therefore, it is a colorless liquid or crystalline solid ( below 63F ) with an aromatic.! Aliphatic hydrocarbons by free radical catalyzed processes, as defined ask a question, provide feedback, or report problem! Related substance of the standard enthalpies of formation of polychlorobenzenes frequently used to produce dyes and textiles a,... Spectrophotometers for water analysis based upon an estimated Henry & # x27 ; s Law in. Products like Stericup and Millex filters data under the IRIS Program 1,3,5-trichlorobenzene are colorless,!
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